A former drug addict turned behavioural neuroscientist reveals how drugs work in the brain – and what we can do to fight addiction. Judith Grisel was a daily drug user when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Delving into the science of one of the world’s most pressing health problems, she reveals what is different about the brains of addicts even before they first pick up a drink or drug, and highlights the changes that take place in the